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肾病患者肌酐偏高或偏低的原因

来源:华人健康网 | 发布时间:2011-08-13 13:15:22 | www.chinesejk.com
肾病患者在临床检查中会出现肌酐的波动,表现为血肌酐高于正常值,而尿肌酐低于正常值。
这是由于肾脏在受到各种病因的侵犯后,先是受损的肾脏固有细胞发生表型转化,形成病理变化,刺激肾脏内成纤维细胞转化成肌成纤维细胞,又同时侵犯并激发了固有的正常肾组织,发生同样的病变,从而形成了肾脏由点到面,由局部到整体的,扩大激发式的蔓延过程,从而进入了器质损伤期(即肾功能损伤期),此时由于肾脏不断造成损伤,其排泄废物的功能有所降低,就造成了肌酐等毒素在体内的聚集,从而出现血内肌酐、尿素氮升高,尿中肌酐下降,双肾滤过率下降等。同时患者还会有高血压、高度浮肿等身体其他症状。

(编辑:小鱼 )

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